GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs3105593 | 1 | rs3109878 | chr15:50836243 | SPPL2A | chr15:50999739-51057910:- | 0.23 | 4.27 | 2.42E-5 | QT interval |
| BLCA | cis | rs7655841 | 1 | rs3113489 | chr4:129961179 | C4orf33 | chr4:130014829-130033842:+ | -0.33 | -5.43 | 9.9E-8 | Chronic obstructive pulmonary disease (moderate to severe) |
| BLCA | cis | rs7849270 | 1 | rs3124510 | chr9:131899690 | CRAT | chr9:131857075-131873070:- | -0.32 | -5.83 | 1.19E-8 | Blood metabolite ratios |
| BLCA | cis | rs7849270 | 1 | rs3124512 | chr9:131903881 | CRAT | chr9:131857075-131873070:- | -0.35 | -6.08 | 2.93E-9 | Blood metabolite ratios |
| BLCA | cis | rs2243480 | 1 | rs313798 | chr7:65493031 | CCT6P1 | chr7:65216092-65228661:+ | 0.32 | 4.4 | 1.43E-5 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs313799 | chr7:65494330 | CCT6P1 | chr7:65216092-65228661:+ | 0.3 | 4.32 | 1.97E-5 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs313802 | chr7:65516373 | CCT6P1 | chr7:65216092-65228661:+ | 0.31 | 4.19 | 3.41E-5 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs313803 | chr7:65514731 | CCT6P1 | chr7:65216092-65228661:+ | 0.31 | 4.19 | 3.41E-5 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs313807 | chr7:65499481 | CCT6P1 | chr7:65216092-65228661:+ | 0.3 | 4.32 | 1.97E-5 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs313809 | chr7:65499983 | CCT6P1 | chr7:65216092-65228661:+ | 0.31 | 4.39 | 1.48E-5 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs313814 | chr7:65503293 | CCT6P1 | chr7:65216092-65228661:+ | 0.31 | 4.23 | 2.93E-5 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs313820 | chr7:65574466 | CCT6P1 | chr7:65216092-65228661:+ | 0.35 | 4.95 | 1.13E-6 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs313824 | chr7:65581207 | CCT6P1 | chr7:65216092-65228661:+ | 0.35 | 4.95 | 1.13E-6 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs313831 | chr7:65551226 | CCT6P1 | chr7:65216092-65228661:+ | 0.35 | 4.8 | 2.27E-6 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs313832 | chr7:65550891 | CCT6P1 | chr7:65216092-65228661:+ | 0.35 | 4.8 | 2.27E-6 | Diabetic kidney disease |